Grandfather Stefano Brunetto opened the first Mona Lisa Restaurant in downtown San Diego in 1956. In 1973, we opened our Little Italy restaurant and deli. It was also a wholesale import business in it…
We got the #8 and #18. Both sandwiches are unbelievable! Fresh ingredients and the meats are so flavorful. Great balance of flavors.
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Kristina K
7 contributions
Loved
• 6/14/26
• DoorDash order
I have lived in SD since 1989 and heard about Mona Lisa Deli sandwiches, but the idea never enticed me. But today, I decided to try its sandwiches for the first time, with hesitant reservation. Gotta say, these are the best deli sandwiches I have ever tasted in San Diego, hands down. The deluxe #8 is best, and the Caprese, equally good, after adding a little salt. I think I found my favorite deli shop in SD and will order sandwiches only from Mona Lisa Deli from now on.
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Michelle D
2 contributions
Loved
• 4/9/26
• DoorDash order
Honestly, I would've taken a picture if it didn't look so good. I had to dive in. The sandwich had so much flavor and it was big enough for me to share! Definitely going to order Mona Lisa's again. I'm sure everything on their menu is great.
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Sebastian S
Emerging Expert • 4 contributions
Loved
• 2/27/24
• DoorDash order
Hands down top 3 favorite subs in San Diego, semolina bread and freshly sliced deli meat cant be faked. This place is legit!
L
Larissa F
5 contributions
Loved
• 12/19/25
• DoorDash order
I looooove this place! I can't eat mayo tho, and they didn't previously allow edits to items, so I've never been able to order from here on DoorDash. I submitted a request to allow this so that I can order from here on DoorDash and they approved it and quickly updated the site! Amazing food, amazing staff, amazing all around. I get the spicy sandwich!
The most commonly ordered items and dishes from this store
Sandwich
Please specify any items removed from your order. All Sandwich includes, Lettuce, Tomato, Red Onion, Salt, Black Pepper, Italian Salad Dressing, Mayonnaise, and Yellow Mustard.
